Searchable abstracts of presentations at key conferences in endocrinology

ea0063p409 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Diagnostic accuracy of the aldosterone to active renin ratio in detecting primary aldosteronism: the graz endocrine causes of hypertension (GECOH) study

Pilz Stefan , Keppel Martin , Trummer Christian , Theiler-Schwetz Verena , Pandis Marlene , Borzan Valentin , Pittrof Matthias , Obermayer-Pietsch Barbara , Grubler Martin R , Verheyen Nicolas , Stepan Vinzenz , Meinitzer Andreas , Voelkl Jakob , Marz Winfried , Tomaschitz Andreas

Context: The aldosterone to active renin ratio (AARR) is the recommended screening test for primary aldosteronism (PA), but prospective study data on its sensitivity and specificity are sparse.Objective: We investigated the diagnostic accuracy of the AARR for detecting PA.Design: This is a prospective diagnostic accuracy study.Setting: This study was conducted from February 2009 to August 2015 at the outpatie...

ea0056p308 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2018

Soluble ST2, a promising cardiovascular biomarker, is associated with parameters of glucose and bone metabolism in subjects at cardiovascular risk

Francic Vito , Gaksch Martin , Schwetz Verena , Trummer Christian , Pandis Marlene , Aberer Felix , Grubler Martin , Verheyen Nicolas D , Marz Winfried , Pieber Thomas R , Tomaschitz Andreas , Pilz Stefan , Obermayer-Pietsch Barbara

Introduction: Soluble ST2 (sST2) is the truncated soluble form of the ST2 receptor in the circulation. It is a decoy receptor of IL-33 and thereby inhibits the effects of IL-33/ST2 signaling. Elevated levels of sST2 have been associated with various adverse cardiovascular outcomes. Recently, potential associations of sST2 with obesity and type 2 diabetes mellitus (T2DM) have been described in the general population. In this study, we determined possible cross-sectional associa...